strains of the propionibacterium acnes type iii lineage

Utility of strain typing of Propionibacterium acnes in

Available frozen isolates were recovered,and strain type (IA-1,IA-2,IB,II,III,or nontypeable class A or B) was determined via polymerase chain reaction (PCR)-based methods.For CNS isolates,P.acnes was considered pathogenic if treating physicians administered 7 days of directed antibiotic therapy against P.acnes.The diversity and host interactions of Propionibacterium We found that the outcome of the bacteriumphage interactions is P.acnes lineage dependent.All type I P.acnes strains (clades IA-1,IA-2,IB-1 and IB-2) except clade IB-3 were susceptible to The Skin Microbiome A New Actor in Inflammatory Acne Sep 10,2020 strains of the propionibacterium acnes type iii lineage#0183;Furthermore,strains of the C.acnes type III lineage have been shown to be associated with progressive macular hypomelanosis .The Gut Microbiome Interacts with the Skin Microbiome in Acne.The interactions between the bacteria involved in acne extend beyond the skin itself.

The Skin Microbiome A New Actor in Inflammatory Acne

Sep 10,2020 strains of the propionibacterium acnes type iii lineage#0183;Furthermore,strains of the C.acnes type III lineage have been shown to be associated with progressive macular hypomelanosis .The Gut Microbiome Interacts with the Skin Microbiome in Acne.The interactions between the bacteria involved in acne extend beyond the skin itself.Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosisAbstract.Progressive macular hypomelanosis (PMH) is a common skin disorder that causes hypopigmentation in a variety of Introduction.The common and worldwide skin Author:Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,SheilaCited by:25Publish Year:2016Strains of the Propionibacterium acnes type III lineage Was this helpful?People also askWhat is Propionibacterium acnes?What is Propionibacterium acnes?Footnote Propionibacterium acnes induces the production of AMP,TLRs,cytokines,PARs,MMP,IL-1a,CAMP,hyaluronate lyase,and porphyrins,resulting in the formation of inflammatory acne lesions.It modulates the differentiation of keratinocytes by inducing keratin 10,filaggrin,and desmocollin 1 expression.Propionibacterium acnes,infection,symptoms treatmentSome results are removed in response to a notice of local law requirement.For more information,please see here.Previous123456NextStrains of the Propionibacterium acnes type III lineage Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis By Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,Sheila Patrick and Andrew McDowell

Some results are removed in response to a notice of local law requirement.For more information,please see here.Proposal to reclassify Propionibacterium acnes type I as

2 Abstract 26 27 Recently,strains of Propionibacterium acnes from the type III genetic division have been 28 proposed as Propionibacterium acnes subsp.elongatum subsp.nov.,with strains from the 29 type I and II divisions collectively classified as Propionibacterium acnes subsp.acnes subsp.30 nov.Under such a taxonomic re-appraisal,we believe that types I and II should also havePropionibacterium acnes,infection,symptoms treatmentDifferent Propionibacterium acnes types have been isolated from acne vulgaris,and the type III strains have been associated with progressive macular hypomelanosis,underscoring the importance of genetic division of Propionibacterium acnes and suggesting the involvement of specific Propionibacterium acnes phylotypes in the pathophysiology of

Propionibacterium acnes phylogenetic type III is

Barnard E,Liu J,Yankova E,Cavalcanti SM,Magalhaes M,Li H,Patrick S,McDowell A Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis.Sci Rep 6,31968 (2016)Propionibacterium acnes phylogenetic type III is Barnard E,Liu J,Yankova E,Cavalcanti SM,Magalhaes M,Li H,Patrick S,McDowell A Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis.Sci Rep 6,31968 (2016)Propionibacterium acnes Strains Differentially Regulate Agak et al.demonstrate that different strains of Propionibacterium acnes,a bacterium colonizing pilosebaceous units in healthy skin and acne,have the ability to induce T helper type 17 cells secreting either IFN- or IL-10 and exhibiting either pathogenic or protective properties,respectively.This work contributes to growing evidence indicating that the phenotype of T helper type 17

Propionibacterium acnes Strain Populations in the Human

Sep 01,2013 strains of the propionibacterium acnes type iii lineage#0183;Genome comparison of 71 Propionibacterium acnes strains showed that the genomes of ribotypes 4 and 5 (RT4 and RT5) are distinct from those of others.Two chromosomal regions,loci 1 and 2,are unique to clade IA-2 and one other genome HL086PA1.Propionibacterium acnes Disease-Causing Agent orPropionibacterium acnes is the most abundant bacterium on human skin,particularly in sebaceous areas.P.acnes is suggested to be an opportunistic pathogen involved in the development of diverse medical conditions but is also a proven contaminant of human clinical samples and surgical wounds.Its significance as a pathogen is consequently a matter of debate.Propionibacterium Acnes Phylogenetic Type III is Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis Emma Barnard ,Jared Liu ,

Porphyrin Production and Regulation in Cutaneous

ized porphyrin production in all lineages of Propionibacterium acnes,the most domi-nant skin Propionibacterium,and other resident skin propionibacteria,including P.granulosum,P.avidum,and P.humerusii.We revealed that P.acnes type I strains pro-duced signicantly more porphyrins than did type II and III strains and other Propi Porphyrin Production and Regulation in Cutaneous Eleven Propionibacterium strains were cultured on solid A-medium plates,including P.acnes type I (HL037PA1,KPA171202,and PV66),type II (HL00PA1,HL042PA3,and HL110PA3),and type III (HL201PA1 and BR-16) strains,as well as P.granulosum (HL082PG1),P.avidum (HL307PV1),and P.humerusii (HL044PA1) strains.Plates were incubated for 5 to 7 Pan-Genome and Comparative Genome Analyses of To cover all the main P.acnes lineages in the analysis,we newly sequenced three additional P.acnes strains,including the first available type III P.acnes genome.Thirteen P.acnes genomes sequenced by other research groups ( 14 ,17 22 ) were also available at the time of analysis.

Pan-Genome and Comparative Genome Analyses of

To cover all the main P.acnes lineages in the analysis,we newly sequenced three additional P.acnes strains,including the first available type III P.acnes genome.Thirteen P.acnes genomes sequenced by other research groups ( 14 ,17 22 ) were also available at the time of analysis.Microorganisms Free Full-Text Propionibacterium acnes The anaerobic bacterium Propionibacterium acnes is believed to play an important role in the pathophysiology of the common skin disease acne vulgaris.Over the last 10 years our understanding of the taxonomic and intraspecies diversity of this bacterium has increased tremendously,and with it the realisation that particular strains are associated with skin health while others appear related to Genotypic and Antimicrobial Characterisation of 1.Introduction.As a member of the normal skin and oral microbiota,Propionibacterium acnes (P.acnes) is frequently dismissed as a contaminant of clinical samples.While a likely pathogenic role in the inflammatory skin condition acne vulgaris has been well documented [],evidence is now emerging that suggests P.acnes is important in a number of other infections and clinical conditions.

Emendation of Propionibacterium acnes subsp.acnes

Recently,it has been proposed that strains of Propionibacterium acnes from the type III genetic division should be classified as P.acnessubsp.elongatum subsp.nov.,with strains from the type I and II divisions collectively classified as P.acnessubsp.acnes subsp.nov.Under such a taxonomic re-Editorial Propionibacterium acnes in Human Health andunique to the strain; type IB strains have rarely been isolated fromacnelesions.Collectively,thispaperprovidesadditional data on P.acnes virulence properties and host adaptation mechanisms that may be relevant to our understanding of acnepathogenesis.Stillonthethemeofacne,E.A.Eadyetal.in a second review paper hypothesise thatDissecting the taxonomic heterogeneity within Propionibacterium acnes subsp.acnes subsp.nov.and Propionibacterium acnes subsp.elongatum subsp.nov.are described.These emanate from the three known phylotypes of P.acnes,designated types I,II and III.Electron microscopy confirmed the filamentous cell shape of type III,showing a striking

Different strains of Propionibacterium acnes modulate

Jun 29,2013 strains of the propionibacterium acnes type iii lineage#0183;P.acnes strains modulate differently the expression of immune markers both at gene and at protein levels.P.acnes type III had the highest proinflammatory potential by upregulating the expression of PAR2,TNFalpha,MMP13 and TIMP2,whereas P.avidum had the weakest by upregulating only MMP13 and TIMP2.Different strains of Propionibacterium acnes modulate Jun 29,2013 strains of the propionibacterium acnes type iii lineage#0183;P.acnes strains modulate differently the expression of immune markers both at gene and at protein levels.P.acnes type III had the highest proinflammatory potential by upregulating the expression of PAR2,TNFalpha,MMP13 and TIMP2,whereas P.avidum had the weakest by upregulating only MMP13 and TIMP2.Different strains of Propionibacterium acnes modulate Jun 29,2013 strains of the propionibacterium acnes type iii lineage#0183;P.acnes strains modulate differently the expression of immune markers both at gene and at protein levels.P.acnes type III had the highest proinflammatory potential by upregulating the expression of PAR2,TNFalpha,MMP13 and TIMP2,whereas P.avidum had the weakest by up

Cited by 73Publish Year 2013Author Fiona Jasson,Istvan Nagy,Anne Chantal Knol,Thomas Zuliani,Amir Khammari,Brigitte Dr strains of the propionibacterium acnes type iii lineage#233;noPropionibacterium Acnes Phylogenetic Type III is

Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis Emma Barnard ,Jared Liu ,+5 authors A.McDowell BiologyCited by 25Publish Year 2016Author Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,SheilaStrains of the Propionibacterium acnes type III lineage Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis./ Barnard,Emma; Liu,Jared; Yankova,Eliza; Cavalcanti,Silvana,M; Magalh strains of the propionibacterium acnes type iii lineage#227;es,Marcelo; Li,Huiying; Patrick,Sheila; McDowell,Andrew.In Scientific Reports,Vol.6,No.31968,24.08.2016.Cited by 25Publish Year 2016Author Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,SheilaStrains of the Propionibacterium acnes type III lineage Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis./ Barnard,Emma; Liu,Jared; Yankova,Eliza; Cavalcanti,Silvana M; Magalh strains of the propionibacterium acnes type iii lineage#227;es,Marcelo; Li,Huiying ; Patrick,Sheila ; McDowell,Andrew.

Cited by 25Publish Year 2016Author Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,SheilaStrains of the Propionibacterium acnes type III lineage

Aug 01,2016 strains of the propionibacterium acnes type iii lineage#0183;Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosisCited by 25Publish Year 2016Author Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,SheilaImages of Strains of the Propionibacterium acnes type III line imagesDifferent strains of Propionibacterium acnes modulate P.acnes strains modulate differently the expression of immune markers both at gene and at protein levels.P.acnes type III had the highest pro-inflammatory potential by up-regulating the expression of PAR-2,TNF-alpha,MMP-13 and TIMP-2,whereas P.avidum had the weakest by up-regulating only MMP-13 and TIMP-2.An expanded multilocus sequence typing scheme for The Gram-positive bacterium Propionibacterium acnes is a member of the normal human skin microbiota and is associated with various infections and clinical conditions.There is tentative evidence to suggest that certain lineages may be associated with disease and others with health.We recently descr

Acne,the Skin Microbiome,and Antibiotic Treatment

Jan 10,2019 strains of the propionibacterium acnes type iii lineage#0183;Barnard E,Liu J,Yankova E,Cavalcanti SM,Magalhaes M,Li H,et al.Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis.Sci Rep.2016;6:31968.Article CAS PubMed PubMed Central Google Scholar12345NextStrains of the Propionibacterium acnes type III lineage Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis By Emma Barnard,Jared Liu,Eliza Yankova,Silvana M.Cavalcanti,Marcelo Magalh strains of the propionibacterium acnes type iii lineage#227;es,Huiying Li,Sheila Patrick and Andrew McDowell(PDF) Porphyrin Production and Regulation in Cutaneous Recently,strains of Propionibacterium acnes from the type III genetic division have been proposed as Propionibacterium acnes subsp.elongatum subsp.nov.,with strains from the type I and II

results for this questionWhat is the genome size of Propionibacterium acnes?What is the genome size of Propionibacterium acnes?The number and activity of Propionibacterium acnes bacteria varies according to oxygen supply,nutrient supply and the pH level of the skin.Some acne lesion are colonized by Propionibacterium acnes and others are not.The Propionibacterium acnes genome is 2.5 Mb in size and has been completely sequenced 8).Propionibacterium acnes,infection,symptoms treatment results for this questionHow to treat Propionibacterium acnes?How to treat Propionibacterium acnes?Propionibacterium acnes treatment 1 Topical antiacne agents,such as benzoyl peroxide and/or tretinoin or adapalene gel.New bioactive proteins may also prove successful.2 Low-dose combined oral contraceptive 3 Antiseptic or keratolytic washes containing salicylic acid 4 Light / laser therapyPropionibacterium acnes,infection,symptoms treatment results for this questionFeedbackStrains of the Propionibacterium acnes type III lineage

Aug 24,2016 strains of the propionibacterium acnes type iii lineage#0183;Strains of the Propionibacterium acnes type III lineage are associated with the skin condition progressive macular hypomelanosis Abstract.Progressive macular hypomelanosis (PMH) is a common skin disorder that causes hypopigmentation in a variety of Introduction.The common and worldwide skin

results for this questionCan bacteria cause acne lesions?Can bacteria cause acne lesions?The Propionibacterium acnes bacteria can produce active enzymes and innate inflammatory mediators and these may contribute to the activity of acne in some patients.Activation triggers expression of immune response genes.Inflammatory mediators detected in acne lesions colonised by Propionibacterium acnes include:Propionibacterium acnes,infection,symptoms treatment

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